Kuven Moodley
St George's Hospital, LondonLondon, United Kingdom
SEARCH RESULTS
331121 RESULTS
Does It Fly? Study Uncovers Genetic Influence on Brain Function
RESEARCH NEWS 2011-11-02 Research News It does not take much to tilt the biochemical balance needed for optimal brain function. Take brain-derived neurotrophic factor (BDNF); changes in the levels of this trophic factor, or its activity, can make the difference between a neuron’s
Pfizer Halts Development of Aβ Antibody
RESEARCH NEWS 2011-11-02 Research News Pfizer Inc. has halted development of ponezumab, a passive immunotherapy targeting the C-terminal end of amyloid-β (Aβ). “Based on recent data from the ongoing studies, Pfizer has decided not to initiate further development of ponezumab in m
The Life and Times of the Human Brain Transcriptome
RESEARCH NEWS 2011-11-02 Research News Adapted from a story that originally appeared on the Schizophrenia Research Forum. 2 November 2011. A dynamic view of transcription in the human brain has been revealed in two papers published in Nature on 26 October 2011. Both studies track
PAPER Tosun D, Rosen H, Miller BL, Weiner MW, Schuff N
MRI patterns of atrophy and hypoperfusion associations across brain regions in frontotemporal dementia.
Neuroimage. 2012 Feb 1;59(3):2098-109. PubMed: 22036676PAPER Tartaglia MC, Zhang Y, Racine C, Laluz V, Neuhaus J, Chao L, Kramer J, Rosen H, Miller B, Weiner M
Executive dysfunction in frontotemporal dementia is related to abnormalities in frontal white matter tracts.
J Neurol. 2011 Oct 29; PubMed: 22037958PAPER Van Langenhove T, van der Zee J, Engelborghs S, Vandenberghe R, Santens P, Van den Broeck M, Mattheijssens M, Peeters K, Nuytten D, Cras P, De Deyn PP, De Jonghe P, Cruts M, Van Broeckhoven C
Ataxin-2 polyQ expansions in FTLD-ALS spectrum disorders in Flanders-Belgian cohorts.
Neurobiol Aging. 2012 May;33(5):1004.e17-20. PubMed: 22035589PAPER Jeong JK, Seo JS, Moon MH, Lee YJ, Seol JW, Park SY
Hypoxia-inducible factor-1 alpha regulates prion protein expression to protect against neuron cell damage.
Neurobiol Aging. 2011 Oct 28; PubMed: 22036844PAPER Xu T, Gong Z, Zhu WZ, Wang JF, Li B, Chen F, Deng XM
Remote ischemic preconditioning protects neurocognitive function of rats following cerebral hypoperfusion.
Med Sci Monit. 2011 Nov;17(11):BR299-304. PubMed: 22037731PAPER Badiola N, de Oliveira RM, Herrera F, Guardia-Laguarta C, Gonçalves SA, Pera M, Suárez-Calvet M, Clarimon J, Outeiro TF, Lleó A
Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy.
PLoS One. 2011;6(10):e26609. PubMed: 22039514PAPER Lomazzo E, Hussmann GP, Wolfe BB, Yasuda RP, Perry DC, Kellar KJ
Effects of chronic nicotine on heteromeric neuronal nicotinic receptors in rat primary cultured neurons.
J Neurochem. 2011 Oct;119(1):153-64. PubMed: 21806615PAPER Spoelgen R, Meyer A, Moraru A, Kirsch F, Vogt-Eisele A, Plaas C, Pitzer C, Schneider A
A novel flow cytometry-based technique to measure adult neurogenesis in the brain.
J Neurochem. 2011 Oct;119(1):165-75. PubMed: 21812782PAPER Xu X, Warrington AE, Wright BR, Bieber AJ, Van Keulen V, Pease LR, Rodriguez M
A human IgM signals axon outgrowth: coupling lipid raft to microtubules.
J Neurochem. 2011 Oct;119(1):100-12. PubMed: 21824142PAPER Blugeot A, Rivat C, Bouvier E, Molet J, Mouchard A, Zeau B, Bernard C, Benoliel JJ, Becker C
Vulnerability to depression: from brain neuroplasticity to identification of biomarkers.
J Neurosci. 2011 Sep 7;31(36):12889-99. PubMed: 21900567PAPER Chorin E, Vinograd O, Fleidervish I, Gilad D, Herrmann S, Sekler I, Aizenman E, Hershfinkel M